The man convicted over the 2010 murder of multi-millionaire Craig Puddy is reportedly considering a fresh appeal in the wake of a DNA scandal at the state's forensic laboratory.
Cameron Mansell was jailed for life in 2011 for murdering Mr Puddy, whose body has never never found.
Prosecutors alleged Mr Puddy, 45, was killed at his Mt Pleasant home in May after he was confronted by Mansell, who he employed at a bar, about stolen money.
However, Mansell's lawyers argued during the trial that he was at Mr Puddy's home when three thugs entered and killed Mr Puddy over a drug debt and then framed their client for the murder.
Mansell is serving a minimum of 18 years in jail for the murder.
According to the ABC's 7.30 Report, Mansell has written to his Perth lawyer Tim Saayman in which he raises new concerns about DNA material used in the case against him.
It follows revelations that one of the state's top DNA scientists was sacked for "cutting corners" during testing.
Laurence Webb was reportedly involved in analysing DNA samples for dozens of major cases, including Mansell's.
Mr Webb also gave evidence at Mansell's trial in 2011.
"We need to remember there was a jury, that after hearing this large volume of evidence, they spent two full days on either side of the weekend trying to come to a verdict," Mr Saayman told the 7.30 Report.
"There was obviously some discussion going on in there.
"Some people weren't necessarily convinced even with the DNA material. Take out the DNA material, what would have happened?"
WAtoday has contacted Mr Saayman for further comment.
The Public Sector Commission, the North Metropolitan Health Service and the Corruption and Crime Commission have begun three separate inquires into the PathWest scandal.
Mansell failed in a bid to seek leave to appeal in the High Court in 2013 after a previous unsuccessful one in the WA Court of Appeal in relation to the murder.
The story Cameron Mansell considering new Puddy murder appeal after DNA bungle first appeared on WA Today.